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. 2024 Aug 12;29(6):1161–1173. doi: 10.1007/s10741-024-10424-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Non-linear association between spot urine sodium concentration 2 hours after diuretic dosing and total urinary sodium excretion at 6 hours. At lower values, 2-h spot urine sodium may be linear with 6-h urine sodium excretion. At lower values of 2-h spot urine sodium the relationship with 6-h urinary sodium excretion may be linear. However, this relationship appears to not be linear at higher 2-h urinary sodium concentrations, thereby making it harder to predict natriuresis from urine sodium alone. Data adapted from reference [61]