Table 2.

Guideline recommendations for diuretic titration and intensification in ADHF

COR	LOE	Recommendations
2022 ACC/AHA/HFSA Guideline for the Management of Heart Failure
2a	B-NR	In patients hospitalized with HF when diuresis is inadequate to relieve symptoms and signs of congestion, it is reasonable to intensify the diuretic regimen using either (a) higher doses of intravenous loop diuretics or (b) addition of a second diuretic
2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure
2a	B	A combination of a loop diuretic with a thiazide-type diuretic should be considered in patients with resistant edema who do not respond to an increase in loop diuretic doses

COR class of recommendation, LOE level of evidence