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. 2024 Oct 5;14:23187. doi: 10.1038/s41598-024-74497-z

Table 4.

Receiver operating characteristic analysis for each parameter in differentiating KCS from KC.

AUROC 95% CI Cutoff Sensitivity (%) Specificity (%)
Scansys
 KCP 0.983 0.940–0.998 > 69.25 96.08 95.77
Pentacam
 BAD-D 0.999 0.969–1.000 > 4.195 98.04 100
 IS-value 0.967 0.918–0.991 > 1.935 92.16 95.77
 KISA 0.981 0.938–0.997 > 42.642 94.12 94.37
 ISV 0.995 0.961–1.000 > 37 100 95.77
 IVA 0.994 0.960–1.000 > 0.315 96.08 95.77
 KI 0.986 0.946–0.999 > 1.095 94.12 94.37
 CKI 0.955 0.902–0.984 > 1.025 90.20 97.18
 IHA 0.823 0.748–0.899 > 11.55 82.35 71.83
 IHD 0.996 0.962–1.000 > 0.0425 96.08 98.59
Corvis ST
 CBI 0.984 0.942–0.998 > 0.69 98.04 92.96
 TBI 0.861 0.794–0.927 > 0.999 94.12 74.65
 SPA1 0.903 0.846–0.959 ≤ 82.846 86.27 85.92
 DA ratio (2 mm) 0.868 0.798–0.939 > 5.039 76.47 88.73
 Integrated radius 0.906 0.852–0.959 > 10.074 80.39 88.73

KCS keratoconus suspect, KC keratoconus, AUROC area under the receiver operating characteristic curve, CI confidence interval.