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. 2024 Sep 24;24(3):489–499. doi: 10.1007/s40268-024-00491-5
Patients with AML exhibit high variability in response to drugs such as trametinib
RAS status alone is not predictive of trametinib sensitivity in AML blasts
High expression of myeloid differentiation genes, such as CD14, is strongly predictive of trametinib sensitivity in AML blasts