TABLE 1.
Genes altered in expression following TG explantation
| Gene | GenBank accession no. | Change in expression level (fold) |
|---|---|---|
| Induced genes | ||
| Cell surface glucoprotein MUC18 | AA088962 | 45 |
| Cystathione gamma-lyase | AA245993 | 24 |
| Cytochrome P450 | AA266005 | 23 |
| Similar to human acidic ribosomal protein P1 | AA067662 | 20 |
| Retinoid X receptor interacting protein | AA242625 | 19 |
| Aldehyde dehydrogenase | AA469589 | 17 |
| Similar to calcineurin B subunit isoform 1 | AA537502 | 14 |
| Pseudo-prolactin receptor | AA244758 | 11 |
| Metallothionein-I | AA051654 | 10 |
| Transcription factor S-II | AA237509 | 9 |
| B-cell lymphoma 3-encoded protein (Bcl-3) | AA266002 | 8 |
| Zinc finger protein | AA414512 | 8 |
| Prostaglandin endoperoxide | AA245992 | 7 |
| Cyclin-dependent kinase homolog | AA117324 | 7 |
| Aldose 1-epimerase precursor | AA245672 | 7 |
| Uricase | AA244961 | 7 |
| Similar to human Ras-related protein RAB-4 | AA445222 | 6 |
| Glutathione S-transferase | AA445233 | 6 |
| Alpha-N-acetylglucosaminidase | AA268207 | 6 |
| Ubiquitin-conjugating enzyme E2-18 KD | AA238200 | 6 |
| Protein phosphatase type 1 | AA518429 | 5 |
| MHC class I Qa-Tla | AA051194 | 5 |
| Q7(b) cell surface antigen | AA174486 | 5 |
| GTPase-activating protein GAPIII | W33527 | 5 |
| Primase large subunit | AA237894 | 4 |
| Similar to human gamma interferon inducible protein | AA403965 | 4 |
| RNA polymerase II elongation factor SIII, p15 | AA461967 | 4 |
| R-ras | AA522428 | 4 |
| Similar to human RAB-3A | AA445184 | 4 |
| Neural retina-specific leucine zipper protein | AA517895 | 4 |
| LZIP-1 and LZIP-2 | AA266568 | 3 |
| Similar to human GC-rich sequence DNA-binding factor | AA184767 | 3 |
| Cyclin F | AA240462 | 3 |
| Suppressed genes | ||
| Similar to human putative Ser/Thr protein kinase p78 | AA221667 | 84 |
| Plasminogen activator inhibitor 2 | AA124868 | 61 |
| P1 protein, DNA replication factor | W97481 | 47 |
| Dihydroxyphenylacetate oxidase | AA137764 | 30 |
| Carboxylesterase | AA237640 | 30 |
| Similar to human GTPase RHOC | AA221997 | 28 |
| ATP-dependent RNA helicase | AA212347 | 26 |
| Similar to human zinc finger protein 32 | AA462760 | 23 |
| Semaphorin B | AA222348 | 21 |
| Myelin proteolipid protein | AA067291 | 20 |
| Semaphorin D | W98303 | 19 |
| B-myb | AA432951 | 12 |
| Synaptogyrin | AA275862 | 12 |
| Kinesin-related protein | AA261010 | 11 |
| Similar to human transaldolase | AA543582 | 10 |
| Hsp70-related NST-1 | AA119654 | 10 |
| Short-chain acyl-coenzyme A dehydrogenase | AA414061 | 10 |
| Transforming growth factor beta-3 | AA103431 | 9 |
| Similar to human dihydrolipoamide | ||
| Succinyltransferase | AA220084 | 7 |
| Myelin gene expression factor | AA210564 | 7 |
| Ras-related YPT1 | AA290385 | 6 |
| Malonyl-coenzyme A decarboxylase precursor | AA238355 | 6 |
| IGF-II | AA103939 | 6 |
| PML isoform 1 | AA138191 | 5 |
| Metalloproteinase inhibitor 3 precursor | AA423441 | 5 |
| Serine/threonine protein kinase | AA511351 | 5 |
| Interferon regulatory factor 3 | AA103471 | 5 |
| Retinoic acid-responsive protein | AA222497 | 5 |
| NCAM-140 and NCAM-180 isoforms | AA039178 | 5 |
| Ubiquitin-activating enzyme | AA221449 | 4 |
| Glutamate dehydrogenase | AA511913 | 4 |
| TEIIIC2 subunit | AA445571 | 4 |
| Transforming growth factor beta-inducible protein | AA034808 | 4 |
| Similar to human serum response factor | AA154152 | 4 |
| Similar to human synaptobrevin 2 | AA036389 | 4 |
| Chromatin nonhistone HMG | AA538243 | 4 |
| Neurofilament triplet M | W64752 | 3 |
| Tumor necrosis factor I receptor | AA003594 | 3 |