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. 2024 Sep 23;15:1457467. doi: 10.3389/fphar.2024.1457467

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Copyright © 2024 Yong, Mimi, Yingjie, Yichen, Yansu, Zhi, Hui, Si, Chongming, Xiaopo, Ning and Weiying.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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RNA-Seq assay of the effects of mangiferin on PCOS. (A) Differential rates of gene expression in PCOS before and after intervention with mangiferin. (B) Volcanic map analysis of differential gene expression before and after treatment with mangiferin. (C) Heatmap of the overall differential gene expression. GO analysis of gene function in (D) biological process, (E) cellular component, (F) molecular function and (G) cellular processes. GSEA analysis of PCOS and (H) mangiferin in apoptosis, (I) necroptosis and (J) inflammatory bowel disease.