Table 1.
Baseline characteristics of the study cohort.
| Variable | Analysis set 779 (100) | Female sex 234 (30) | Male sex 545 (70.0) | p value |
|---|---|---|---|---|
| Recipient | ||||
| Age (y), mean ± SD | 52.2 ± 10.3 | 49.6 ± 11.3 | 53.3 ± 9.7 | <0.001 |
| Weight (kg), mean ± SD | 80.2 ± 16.6 | 70.9 ± 15.4 | 84.1 ± 15.4 | <0.001 |
| BMI (kg m−2), mean ± SD | 26.6 ± 4.8 | 25.9 ± 5.2 | 26.9 ± 4.6 | 0.004 |
| Retransplantation, n (%) | 67 (8.6) | 16 (6.8%) | 51 (9.4%) | 0.250 |
| Child-Pugh, n (%) | ||||
| A | 221 (28.4) | 68 (29.0) | 153 (28.1) | <0.001 |
| B | 214 (27.5) | 41 (17.5) | 173 (31.7) | |
| C | 344 (44.2) | 125 (53.4) | 219 (40.1) | |
| MELD, mean ± SD | 19.3 ± 10.4 | 20.5 ± 11.1 | 18.7 ± 10.0 | 0.095 |
| Urgency, n (%) | ||||
| T | 736 (94.5) | 204 (87.1) | 532 (97.6) | <0.001 |
| HU | 43 (5.5) | 30 (12.8) | 13 (2.3) | |
| Medical history, n (%) | ||||
| Previous deep vein thrombosis | 11 (1.4) | 4 (1.7) | 7 (1.2) | 0.645 |
| Previous hepatic artery thrombosis | 11 (1.4) | 5 (2.1) | 6 (1.1) | 0.261 |
| Previous portal vein thrombosis | 84 (10.8) | 27 (11.5) | 57 (10.5) | 0.656 |
| Other thrombosis in history | 107 (13.7) | 37 (15.8) | 70 (12.8) | 0.270 |
| Previous abdominal surgery, n (%) | 275 (35.3) | 104 (44.4) | 171 (31.3) | <0.001 |
| Coronary heart disease, n (%) | 66 (8.47) | 13 (5.5) | 53 (9.7) | 0.055 |
| History of myocardial infarction, n (%) | 20 (2.567) | 4 (1.7) | 16 (2.9) | 0.321 |
| History of stroke, n (%) | 6 (0.77) | 1 (0.4) | 5 (0.9) | 0.473 |
| Donor | ||||
| Age (y), mean ± SD | 58.1 ± 17.3 | 57 ± 19 | 59 ± 16 | 0.453 |
| Female sex, n (%) | 359 (46.1) | 148 (63.2) | 211 (38.7) | <0.001 |
| Weight (kg), mean ± SD | 77.5 ± 15.0 | 69.9 ± 15.2 | 80.7 ± 13.8 | <0.001 |
| BMI (kg m−2), mean ± SD | 26.3 ± 6.1 | 25.3 ± 8.9 | 26.8 ± 4.3 | <0.001 |
| Weight ratio recipient/donor, mean ± SD | 1.1 ± 0.3 | 1.1 ± 0.3 | 1.1 ± 0.2 | 0.030 |
| Surgery data | ||||
| Preoperative hemoglobin (g/dl), mean ± SD | 10.9 ± 2.6 | 10.5 ± 2.8 | 11.0 ± 2.5 | 0.001 |
| Preoperative platelet count, mean ± SD | 119.5 ± 91.3 | 128.9 ± 97.7 | 115.4 ± 88.2 | 0.178 |
| Intraoperative blood loss (ml/kg), mean ± SD | 55.27 ± 57.6 | 55.96 ± 55.6 | 54.5 ± 58.5 | 0.964 |
| Cold ischemia time (h), mean ± SD | 8.6 ± 3.1 | 8.23 ± 3.4 | 8.75 ± 2.9 | 0.117 |
| Surgery time (h), mean ± SD | 5.8 ± 1.5 | 5.7 ± 1.53 | 5.9 ± 1.4 | 0.038 |
Data are presented as mean ± SD, or as absolute number (percentage). SD, standard deviation; BMI, body mass index; MELD, Model for End-stage Liver Disease; T, transplantable; HU, high urgency. Bold face indicates p-values < 0.05.