TABLE 2.

Application of metal oxide-based nanozymes in antibacterial.

Nanozymes	Enzymatic activity	Targets	Antibacterial mechanisms	Applications	References
IONPs	POD	E. coli, S. aureus	Generate OH	Clinical anti-infective treatment	Yu B. et al. (2020)
PDA/Fe3O4	POD	E. coli, S. aureus	Generate OH, PTT	Effective treatment of bacterial infections	Xiao et al. (2022)
rough C-Fe3O4, RCF	POD	E. coli, S. aureus, MRSA	Generate OH, PTT, CDT	Effective treatment of drug-resistant bacterial infections	Liu et al. (2021)
CuxO-PDA	POD	E. coli, S. aureus	Generate ROS	Clinical antibacterial	He et al. (2022)
CeO2/GOx nanoreactor	POD	E. coli, S. aureus	Generate OH	Biosensors, treatment and environmental repair	Qin et al. (2021)
Cu-CeO2 SSE	POD	E. coli, MRSA	Generate ·OH	Accelerates wound healing during antioxidant and tissue healing processes	Jiang et al. (2018)
Cu1.5Mn1.5O4	OXD, POD, GSH-Px	E. coli, MRSA	Generate OH	Treat bacterial infections	Wu et al. (2022)
NiCo2O4	POD	E. coli, S. aureus	Generate ROS, Mechanical damage	Design new engineering antibacterial material	Song G. et al. (2023)
Cu-Fe3O4	POD	E. coli, MRSA	Generate ROS	Resistant to pathogen infection and wound healing	Jin J. et al. (2024)