Table 1.
Organ weights and principal hemodynamic parameters of the left ventricle
| Strain | sham/intact | sham/RDN | ACF/intact | ACF/RDN |
|---|---|---|---|---|
| Organ weight (g) | ||||
| n | 25 | 28 | 25 | 28 |
| Body weight | 438 ± 9.59 | 439 ± 8.25 | 425 ± 8.38 | 418 ± 7.2 |
| Heart weight | 1.62 ± 0.02 | 1.6 ± 0.03 | 2.24 ± 0.03* | 1.95 ± 0.04*† |
| Left atrium | 0.04 ± 0.001 | 0.041 ± 0.001 | 0.074 ± 0.002* | 0.065 ± 0.002*† |
| Left ventricle (with IVS) | 1.22 ± 0.02 | 1.19 ± 0.02 | 1.53 ± 0.02* | 1.36 ± 0.03*† |
| Kidney weight | 1.61 ± 0.03 | 1.65 ± 0.04 | 1.56 ± 0.04 | 1.51 ± 0.02 |
| Lungs weight | 1.81 ± 0.06 | 1.85 ± 0.04 | 2.47 ± 0.12* | 2.1 ± 0.06*† |
| Liver weight | 15.97 ± 0.43 | 15.49 ± 0.4 | 16.6 ± 0.39 | 14.83 ± 0.33† |
| Hemodynamics | ||||
| n | 8 | 11 | 14 | 10 |
| Stroke work (mmHg*µl) | 6957 ± 784 | 7334 ± 646 | 10,757 ± 581* | 7953 ± 841† |
| Cardiac output (μl/min) | 17,305 ± 2052 | 20,426 ± 1193 | 32,205 ± 1843* | 24,544 ± 2765† |
| Stroke volume (μl) | 44.1 ± 4.8 | 49.1 ± 3.5 | 78.9 ± 3.6* | 60.5 ± 6.6† |
| Mean ventricular pressure (mmHg) | 75.4 ± 3.7 | 65 ± 2.2* | 68.4 ± 2.3 | 67.1 ± 2.2 |
| End-systolic pressure (mmHg) | 169 ± 3.7 | 149 ± 3.8* | 143 ± 3.1* | 142 ± 2.2* |
| End-diastolic pressure (mmHg) | 7 ± 0.78 | 5.5 ± 0.63 | 12.7 ± 1.63* | 8.2 ± 0.69† |
| End-diastolic volume (µl) | 230 ± 21.1 | 260 ± 13.3 | 356 ± 13.3* | 264 ± 27† |
| End-systolic volume (µl) | 175 ± 17.9 | 207 ± 6.7 | 260 ± 12.3* | 191 ± 19.3† |
| Heart rate (bpm) | 389 ± 8.5 | 392 ± 7.6 | 384 ± 6.5 | 403 ± 3.5 |
Values are means ± SEM
*p < 0.05 vs. sham/intact; †p < 0.05 vs. ACF/intact