TABLE 2.

Conserved microRNA and their putative or validated roles in hard ticks, mosquitoes, and Drosophila.

Species	Role	Sequence	References
miR-1
Hyalomma anatolicum	∆ Development/Feeding	N/A	Luo et al. (2021)
Drosophila	∆ Development	CCA​UGC​UUC​CUU​GCA​UUC​AAU​A	Sokol and Ambros (2005)
Let-7
Hyalomma asiaticum	Molting	N/A	Wu et al. (2019)
Anopheles gambiae	Immunity	UGA​GGU​AGU​UGG​UUG​UAU​AGU	Fu et al. (2020)
Drosophila	∆ Development	UGA​GGU​AGU​AGG​UUG​UAU​AGU	Sempere et al. (2002), Sokol et al. (2008)
miR-375
Haemaphysalis longicornis	*Oviposition and hatchability	N/A	Malik et al. (2019a)
Aedes aegypti/Aag 2 cell line	∆Development/pathogen transmission	UUU​GUU​CGU​UUG​GCU​CGA​GUU​A	Hussain et al. (2013)
Drosophila	Olfactory memory	ACU​UGG​GCC​AAG​GGA​AUG​CAA​ACU	Rahman et al. (2020)
miR-275
Haemaphysalis longicornis	Reproductive development/Blood digestion	N/A	Hao et al. (2017)
Aedes aegypti	Egg development/blood digestion	CGC​GCU​AAG​CAG​GAA​CCG​AGA​C	Zhao et al. (2017), He et al. (2021)
Drosophila	Male spermatid maturation	CGC​GCU​AAU​CAG​UGA​CCG​GGG​CU	Eun et al. (2013)
miR-71
Ixodes scapularis	*Pathogen replication	UGA​AAG​ACA​UGG​GUA​GUG​AGA​UG	Kumar et al. (2022)
Culex pipiens pallens	Pesticide resistance	N/A	Guo et al. (2017)
Drosophila	∆ Development	N/A	Leaman et al. (2005)