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. 2024 Oct 6;15:8658. doi: 10.1038/s41467-024-52666-y

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — A (LEFT) Representative OCR (Oxygen Consumption Rate) data measured using Seahorse for CD19 ± GLUT1OE or for HA ± GLUT1OE on day 12. (RIGHT) Pool data for Basal and Maximum OCR and SRC (Spare Respiratory Capacity) from three independent experiments with n = 6 donors. P values determined by paired two-tailed t-tests. Error bars represent SD. B (TOP) Mitochondrial mass and (BOTTOM) potential detected using Mitotracker Green and Deep Red, respectively in HA ± GLUT1OE CAR-T cells on day 9 with representative histograms shown. Data from n = 3 donors. P values determined by paired two-tailed t-tests. Error bars represent SD. C (TOP) Mitochondrial mass and (BOTTOM) potential detected using Mitotracker Green and Deep Red, respectively in CD19 ± GLUT1OE CAR-T cells on day 9 with representative histograms shown. Data from n = 3 donors. P values determined by paired two-tailed t-tests. Error bars represent SD.