In vitro anti-proliferative activity of twenty-six final compounds against three human cancer cell lines MCF-7, HepG2, HEp-2 and a normal Vero cell line at a single concentration of 100 μg mL−1a.
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Vero: normal African green monkey kidney cell line; HepG2: human liver carcinoma cell line; HEp-2: human laryngeal carcinoma cell line; MCF-7: human breast carcinoma cell line. Values are the means ± SD of three independent experiments performed in triplicate. Yellow: excellent effect (>75% inhibition), orange: good activity (>70% inhibition), not highlighted moderate effect (50–70% inhibition) and brown: weak activity.