TABLE 4.

Estimated mean differences (HiFlo minus standard care) with bootstrapped 95% confidence intervals for candidate outcomes

Outcome	n	Estimated difference	95% CI
Treatment failure needing escalation of therapy, %	50	−23	−46–0
Time to meeting discharge criteria, h	50	−5.5	−20.3–9.2
Time to actual hospital discharge, h	50	−1.8	−17.4–13.9
Time to achieving PRAM score 3 or less, h	41	1.5	−1.4–8.5
Time to no longer requiring oxygen or respiratory support, h	37	10.8	2.5–19.1

HiFlo: high-flow humidified oxygen; PRAM: Paediatric Respiratory Assessment Measure.