Table 3.

Characteristics before and after oxycodone administration

Case	Starting dosage (mg/day)	Maintenance dosage (mg/day)	Elapsed time until MBS improved well	MBS score		sBP (mmHg)		Heart rate (bpm)		Respiratory rate (bpm)		Adverse effect	Period of administration (day)	Reasons for termination
				Before	After	Before	After	Before	After	Before	After
1	10	10	2 days	10	2	111	94	86	100	25	16	Constipation, nausea, tremor	12 days	Improved
2	10	10	7 days	10	2	80	100	110	90	15	20	None	29 days	Improved
3	6.6	10	2 days	9	8	98	113	103	108	19	26	None	4 days	Death
4	5	10	2 days	10	7	111	102	80	54	23	16	None	6 days	Death
5	5	5	1 day	8	3	85	80	133	102	18	18	PT-INR prolonged, tremor	10 days	Improved
6	7.5	7.5	1 day	10	2	102	111	95	78	26	20	None	35 days	Death
7	6	6	2 h	7	1	99	107	94	92	22	18	Tremor	8 days	Improved
8	10	10	2 days	7	3	129	115	71	72	23	20	None	23 days	Death

MBS Modified Borg scale, sBP Systolic blood pressure, PT-INR International normalized ratio of prothrombin time, Before Before oxycodone administration, After When MBS scores had improved