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. 2024 Aug 6;9(18):e179292. doi: 10.1172/jci.insight.179292

Figure 5. Inflammatory signaling axes are active in vaccine- and tadalafil-treated groups.

Figure 5

(A) Binary heatmap showing active receptors in cells by treatment group (n = 3). (B) Circos plots showing ligands of Cxcr3, Il12rb2, Notch1, and Notch2 and their cellular sources. Thickness of lines correlates to ligand expression levels; thicker lines correspond to higher expression. (C) Heatmap showing expression levels of selected ligands in DCs, endothelial cells, granulocytes, and macrophages.