Figure 2. Human mAb RVFV-268 improves viral control in rats after exposure to aerosolized RVFV.
(A) From 2 low-dose exposure experiments at 3 (B) or 5 (C) dpi, rats pretreated with control (n = 6) or RVFV-268 (n = 6) mAbs were euthanized, and tissue was collected from liver or brain (B) or liver, brain, lung, and spleen (C). Tissue homogenate was used to quantify viral titers by RT-qPCR. Data represent mean ± SEM. Statistics were determined using a 2-way ANOVA. ****P < 0.0001. LOD, limit of detection.