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. 2024 Oct 4;12:e18224. doi: 10.7717/peerj.18224

Table 2. Predicting inaccuracies in LDL-C measurements among intrahepatic cholestatic patients with jaundice: a univariate and multivariate logistic regression analysis.

Characteristics Total(N) Univariate analysis Multivariate analysis
Odds ratio (95% CI) P value Odds ratio (95% CI) P value
Gender 118
Male 63 Reference
Female 55 1.151 [0.543–2.440] 0.714
Age 118 1.019 [0.989–1.049] 0.224
apoA1 118 0.093 [0.020–0.432] 0.002 0.065 [0.001–4.586] 0.208
apoB 118 1.814 [0.762–4.318] 0.178
TC 118 1.281 [1.093–1.503] 0.002 0.542 [0.332–0.885] 0.014
TG 118 1.653 [1.058–2.581] 0.027 3.007 [1.014–8.913] 0.047
HDL-C 118 0.051 [0.010–0.269] <0.001 0.783 [0.010–58.998] 0.912
GGT 118 1.001 [1.000–1.001] 0.137
ALP 118 1.002 [1.001–1.004] <0.001 1.002 [1.000–1.004] 0.036
TB 118 1.015 [1.008–1.023] <0.001 0.985 [0.946–1.026] 0.463
DB 118 1.025 [1.014–1.036] <0.001 1.037 [0.975–1.103] 0.250
TBA 118 1.006 [1.002–1.011] 0.005 1.005 [0.998–1.011] 0.139
AST 118 1.000 [0.997–1.003] 0.889
ALT 118 1.000 [0.997–1.004] 0.863
NH-C/B ratio 118 1.916 [1.291–2.843] 0.001 2.952 [1.359–6.409] 0.006

Note:

Variables with a P-value less than 0.1 in univariate analysis were included in the multivariate logistic regression analysis.

Abbreviations: apoA1, Apolipoprotein A1; apoB, Apolipoprotein B; TC, Total cholesterol; TG, Triglycerides; HDL-C, High-density lipoprotein cholesterol; GGT, Gamma-glutamyl transferase; ALP, Alkaline phosphatase; TB, Total bilirubin; DB, Direct bilirubin; TBA, Total bile acids; AST, Aspartate aminotransferase; ALT, Alanine aminotransferase; NH-C/B Ratio, the ratio of non-HDL-C and APOB ((TC-HDL-C)/APOB).