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. 2024 Oct 4;12:e18220. doi: 10.7717/peerj.18220

Table 2 . Logistic regression of TyG index and incidence of HFpEF.

Characteristic Crude model Model 1 Model 2
OR (95% CI) p-value OR (95% CI) p-value OR (95% CI) p-value
TyG-index 4.739 [3.738–6.082] <0.001 4.842 [3.747–6.344] <0.001 5.127 [3.894–6.856] <0.001
TyG-index (standardization) 3.085 [2.598–3.697] <0.001 3.134 [2.603–3.811] <0.001 3.267 [2.677–4.031] <0.001
TyG-index (categorize)
Tertile 1 Ref Ref Ref
Tertile 2 5.076 [2.534–11.325] <0.001 5.276 [2.585–11.912] <0.001 5.355 [2.587–12.271] <0.001
Tertile 3 30.381 [15.981–65.572] <0.001 32.825 [16.751–72.396] <0.001 34.214 [17.025–77.350] <0.001
p for trend <0.001 <0.001 <0.001

Note:

TyG-index (standardization) means that the mean of the TyG index is changed to 0 and the variance is changed to 1. Crude model adjusted for none. Model 1 adjusted for sex, age, BMI, diabetes, family history of hypertension, diuretics, ACEI/ARB. Model 2 adjusted for Model 1 and laboratory indicators (HDL-C, uric acid, creatinine, TC).