Fig. 5.
Effect of adipose tissue-derived extracellular vesicles (EVs) on interleukin 4 (IL-4) concentration in culture media from Panc02 cells co-cultured with splenocytes. Co-cultures of splenocytes and Panc02 cells were treated with NC-EV (adipose tissue derived extracellular vesicles from C57BL/6J mice) or Ob-EV (adipose tissue derived extracellular vesicles from Ob/Ob mice) and confirmed the level of IL-4. Values are presented as the mean ± SD (n = 3). Con versus groups; #P < 0.05, ##P < 0.01. ***P < 0.001.