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. 2024 Aug 7;228(2):iyae128. doi: 10.1093/genetics/iyae128

Fig. 5.

Fig. 5.

Increased Mcd1 levels partially rescue the growth defect caused by elevated Fdo1 levels. a) Top panel: Growth of 10-fold serial dilutions of wildtype cells overexpressing vector alone (YGS26) and three independent isolates of wildtype cells overexpressing FDO1 (YGS98, YGS100, YGS102). Temperatures and days of growth are indicated. Bottom panel: Growth of 10-fold serial dilutions of wildtype cells overexpressing vector alone (YGS26), eco1Δ rad61Δ double mutant cells overexpressing vector alone (YGS28), and three independent isolates of eco1Δ rad61Δ double mutant cells overexpressing FDO1 (YGS99, YGS101, and YGS103). Temperatures and days of growth are indicated. b) Growth of 10-fold serial dilutions of eco1Δ rad61Δ double mutant cells (YMM828) overexpressing MCD1 (YGS179), overexpressing FDO1 (YGS193), and two independent isolates of eco1Δ rad61Δ co-overexpressing both FDO1 and MCD1 (YGS195, YGS196). Temperature and days of growth are indicated.