TABLE 2.
Characteristics of PROMs Developed After CD Interviews
| Characteristics | PROMs | ||
| HIV-PP-R | HIV-PP-RC | HIV-DAQ | |
| Description | Intended to explore patient perceptions (positive, negative, overall) of current HIV regimen | Intended to explore patient perceptions (positive, negative, overall) of the current (trial) HIV regimen compared with the pretrial HIV regimen | Intended to explore regimen-taking behavior during the course of the trial |
| Concepts covered | 1. “Belief in treatment efficacy” 2. “Use of medication to reduce risk of transmission” 3. “Fear of resistance from poor adherence” 4. “Dosing regimen that fits routine (convenience)” 5. “Reduced preoccupation with regimen-taking” 6. “Fear of disclosure of HIV status” 7. “Medication side effects” 8. “Regimen serving as reminder of HIV status” 9. “Overall burden” 10. “Overall satisfaction” |
1. “Belief in treatment efficacy” 2. “Use of medication to reduce risk of transmission” 3. “Fear of resistance from poor adherence” 4. “Dosing regimen that fits routine (convenience)” 5. “Reduced preoccupation with regimen-taking” 6. “Fear of disclosure of HIV status” 7. “Medication side effects” 8. “Regimen serving as reminder of HIV status” 9. “Overall burden” 10. “Overall satisfaction” |
Part 1: Overall adherence “Overall adherence” “Ease of adherence” “Accidental non-adherence” “Use of a regimen-taking reminder system” Part 2: Factors that made adherence either easy or difficult “Small pill size” “Low-frequency dosing regimen” “Dosing regimen that fits routine (convenience)” “Medication side effects” “Regimen serving as reminder of HIV status” Part 3: Beliefs or feelings that make adherence either easy or difficult “Treatment efficacy,” “Use of medication to reduce risk of transmission” “Fear of resistance from poor adherence” “Fear of disclosure of HIV status” Part 4: Reasons for non-adherence—similar concepts to Parts 2 and 3 |
| Number of items | 10 | 10 | 22 |
| Recall period | 2 wk/4 wk | None | 2 wk/4 wk |
| Sample item | In the past X weeks…has your HIV regimen fit conveniently into your lifestyle? | Which HIV regimen serves as more of a reminder of your HIV status? | In the past X weeks…have you forgotten to take your HIV pills at the day(s) and time(s) that were advised by your health care provider? |
| Sample response options | Not at all; a little bit; somewhat; quite a bit; very much | Current regimen more of a reminder; current and prior regimen similar reminders; prior regimen more of a reminder | Not at all; some of the time; most of the time; all of the time |