Table 3.
SBA titres against MenB strains after three doses of mOMVs.
| Groups | Dose concentration (μg) | N. meningitidis serogroup B strains | |
|---|---|---|---|
| 5/99 fHbp subfamily A (ID23) NadA variant 2/3 NHBA peptide 20 |
M17 240102 fHbp subfamily B (ID13) NHBA peptide 17 |
||
| OMV ID100 NadA | 10 | 32,768 | <8 |
| OMV ID100 NadA | 20 | 32,768 | <8 |
| OMV ID45 NHBA-2 | 10 | 64 | <8 |
| OMV ID45 NHBA-2 | 20 | <8 | <8 |
| OMV ID100 NadA + OMV ID45 NHBA-2 | 10+10 | 16,384 | <8 |
| Alhydrogel only | 0 | <8 | <8 |
It should be noted that the lower limit of quantification for the SBA due to the specified stating dilution is 8. If any samples have SBA titres below 8, this will be reported as <8.