Table 2.

Linear regression coefficients (standard error) of ln-serum neurofilament light chain with a unit increase in ln-urine aromatic amine metabolites in multiple linear regression models, with results weighted for sampling strategy.

Types of aromatic amine	ln sNfL
	Model 1		Model 2		Model 3		Model 4
	β (SE)	p-value	Adjusted β (SE)	p-value	Adjusted β (SE)	p-value	Adjusted β (SE)	p-value
ln 1-AN	0.055 (0.016)	0.004	0.045 (0.024)	0.095	0.045 (0.023)	0.086	0.042 (0.025)	0.155
ln 2-AN	0.100 (0.039)	0.023	0.110 (0.036)	0.015	0.105 (0.034)	0.016	0.111 (0.039)	0.038
ln 4-AN	0.052 (0.019)	0.018	0.061 (0.036)	0.130	0.063 (0.036)	0.124	0.043 (0.030)	0.207
ln o-ANI	0.147 (0.049)	0.009	0.097 (0.041)	0.048	0.096 (0.039)	0.004	0.082 (0.046)	0.132
ln 2,6-Dim	0.029 (0.014)	0.055	0.008 (0.014)	0.576	0.011 (0.014)	0.462	0.008 (0.015)	0.629
ln o-Tol	0.028 (0.040)	0.497	0.050 (0.038)	0.228	0.050 (0.037)	0.227	0.038 (0.042)	0.411

Model 1 unadjusted.

Model 2 adjusted for age, gender, ethnicity, BMI, smoking status, drinking status.

Model 3 adjusted for model 2 plus hypertension.

Model 4 adjusted for model 3 plus Blood lead, ALT, eGFR.