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. 2024 Oct 7;45(1):22. doi: 10.1007/s10875-024-01817-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Representative HE stains and granuloma diameter (A) 20x Lymph node HE stains of representative biopsies of CVID, sarcoidosis (Sarc), PS and TB. (B) Granuloma size per disease group based on the diameter of 30 randomly selected granulomas for each disease group. Median and interquartile ranges are indicated. Kruskal-Wallis with Dunn’s multiple comparison correction, *=P < 0.05, **=P < 0.01, ****=P < 0.0001. (C) Discriminative capacity granuloma sizes to discriminate CVID granulomas from sarcoidosis, PS or TB, shown by ROC analysis. See also Table 2