Fig. 4.

Spatial protein analysis of surrounding areas of granulomas of CVID versus sarcoidosis, PS and TB. (A) Relative protein expression of 72 granulomas, comparing CVID versus sarcoidosis, or PS or TB, with fold induction threshold set to 1 (red line), significance threshold at 1.2 (green line), showing uncorrected P-values. Only significantly altered or borderline significant targets are indicated. (B) Absolute protein counts with median of significantly depleted protein differences in the surrounding areas of CVID versus sarcoidosis, PS or TB. Statistical testing was performed by Kruskall-Walis with Dunn’s multiple comparison correction, * = P ≤ 0.05, ** = P ≤ 0.01, *** = P ≤ 0.001