Table 2.

Discriminative capacity of granuloma size for detecting CVID granulomas

Comparison	Area	cut off size granuloma (µm)	Sensitivity% (95% CI)	Specificity% (95% CI)	LR CVID
CVID vs. Sarc	0.814	< 191	60 (42.3–75.4%)	96.7 (83.3–99.8%)	18
CVID vs. PS	0.842	< 178	56.7 (39.2–72.6%)	96.7 (83.3–99.8%)	17
CVID vs. TB	0.884	< 152	46.7 (30.2–63.9%)	96.7 (83.3–99.8%)	14

CVID = Common Variable Immunodeficiency; PS = pseudo sarcoidosis; TB = tuberculosis. CI = confidence interval. LR CVID = likelihood ratio of being CVID with the cut off size granuloma, sensitivity, specificity and LR derived from ROC analysis