Table 2.

The predicted biochemical properties of the phytochemicals, without cytotoxicity and hepatotoxicity, from ethanolic extract of Adiantum Lunulatum.

Code	Lipinski rule/violation	GI	BBB	A	WS	CT	HT	OT mol/kg	HU	SP (log Kp)
P1	Yes/1	L	N	N	MS	N	N	1.588	0.102	−2.77 cm/s
P2	Yes/1	H	N	N	MS	N	N	1.532	0.244	−3.00 cm/s
P3	Yes/1	L	N	N	MS	N	N	1.663	0.07	−2.49 cm/s
P4	Yes/1	L	N	N	PS	N	N	1.68	0.13	−1.84 cm/s
P5	Yes/1	L	N	N	MS	N	N	1.607	0.05	−2.29 cm/s
P6	Yes/1	L	N	N	PS	N	N	1.615	−0.134	−1.26 cm/s
P7	Yes/1	L	N	N	PS	N	N	1.473	0.272	−1.17 cm/s

Phytochemicals P1 to P7 follow the Lipinski rules with single violation MLOGP>4.15. These phytochemicals GI- Gastrointestinal absorption, BBB-Blood brain barrier permeability, A- AMES toxicity, WS- water solubility, CT- Cytotoxicity, HT-Hepatotoxicity, OT-Oral toxicity LD₅₀ [mol/kg], PS- Poorly soluble, HU- human max tolerated dose log mg/kg/day, SP- Skin permeability were reported. Y-Yes, N-no, L-low, H-High. MS- medium solubility.