Fig. 2.

PRPF8 and RBMX expression in external cohort and association with clinical parameters. (A) PRPF8 (orange) and RBMX (blue) relative mRNA levels in an external validation Pancreatic Ductal Adenocarcinoma (PDAC) cohort (“Jandaghi, 2016”) [20]. Asterisks indicate significant differences between groups by Mann–Whitney U test (**P < 0.01; ***P < 0.001). (B) Distribution of PRPF8 and RBMX Log₁₀ expression levels normalized by ACTB expression levels in the different Histological grades of PDAC in the in‐house cohort. Median and interquartile range are represented. Asterisks indicate significant differences between groups by Dunn's test (*P < 0.05).