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. 2001 Nov;75(21):10208–10218. doi: 10.1128/JVI.75.21.10208-10218.2001

TABLE 3.

Comparison of the binding of MAbs to pH-sensitive epitopes in the prefusion intermediate (pH 5 and 4°C) or the densensitized (pH 5 and 37°C) form of the HA of PR8 virus to the pH 7.5 forma

MAbb Binding to pH 5, 4°C virus/pH 7.5 virus Binding to pH 5, 37°C virus/pH 7.5 virus
Y8 14.0 25.0
H2 3.4 5.4
H3 2.0 5.4
H18 3.2 6.0
H17 0.5 0.16
a

Data from Fig. 9

b

The epitopes of MAbs Y8, H2, H3, and H18 are exposed, and the epitope of H17 is reduced at low pH.