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. 2024 Oct 8;25(1):172. doi: 10.1186/s10194-024-01869-1

Table 1.

Study characteristics

Authors & Year Study Design Sample Size Prevalence Characteristics Treatment Modalities Treatment Outcomes
Olajumoke et al., 2014 Cross-sectional study

402

(168 males and 234 females)

18.9%

(Females 23.7%, Males 5%)

The mean age of onset of migraine headache was 19.2 ± 8.24 years.

Physical activity was the main aggravating factor and occurred in 25% (10/40) of cases.

Migraine headaches showed female preponderance.

The relieving factors were rest in 62.5% (25/40) and over-the-counter analgesics in 17.5% (7/40) of cases.

Simple analgesics, (16.1%)

Nonsteroidal anti-inflammatory drugs (NSAIDs), (19.4%)

Ergotamine derivatives (32.3%)

Amitriptyline, (29%), and

Beta-blockers 1/31 (3.2%)

Not Mentioned
Ekenze et al., 2018 Cross-sectional study. 449 (Females 264; Males 185).

8.9% (10.6% in females and 6.5% in males)

Migraine without aura (73%)

Migraine with aura (27%)

The age range was 19–33 years, with a mean of 23.2 years (males-24.2 and females 22.5) years.

Migraine without aura in this study took the higher proportion of migraine headaches (73%).

The proportion of migraine with aura was 27% of migraine headaches in general.

Not Mentioned Not Mentioned
Ali et al., 2020 Multi-centre, Hospital-based, Cross-sectional study

104

(Males = 27, Females = 74)

69.2%

Migraine with aura 68 (65.4)

Migraine without aura 27 (26)

Migraine with and without aura 9 (8.7)

(Females: 74%; Males 26%)

The mean age at headache onset was 19.3 ± 7.0 years

The mean age at migraine diagnosis was 23.7 ± 6.9 years.

Sixty-nine (66.3%) participants were diagnosed with migraine

within 5 years of headache onset.

Prophylactic medications were used by 26 (45.1%) subjects.

Thirteen (23.6%) subjects were not adherent with preventive drug treatment, while 16 (29%) participants used

their preventive medications acutely.

Propranolol 23 (23.5)

Amitriptyline 39 (39.8)

Sodium valproate 4(4)

Gabapentin 2(2)

Combinations 28(28.6)

Thirty-one (56.4%) sub

jects found preventive medications useful, and 15(27.3%) subjects admitted benefits but with side effects. Seven (12.7%) participants had no benefit from preventative treat

ment, and 9 (16.4%) subjects were classified as refractory

migraine

Birinus et al., 2014 3 Phase Cross-sectional Study

1410

Males were 637(45.2%) and females 773(54.8%)

6.4% (7.5% in females and 5% in males)

Migraine with aura 26(1.8)

Migraine without aura 64(4.5.)

Migraine without aura was significantly higher in females (5.7%) than males (3.1%)

The highest prevalence of migraine occurred among farmers (8.1%)

For 20–29 and the 50-59-year olds, the prevalence of migraine

was similar at 7.1% and 7%, respectively.

Not Mentioned Not Mentioned
Wahab and Ugheoke, 2009 Crosssectional Study

1513

(755 males and 758 females)

9.6% (Females 10.3%, Males 8.9%).

The mean age of all migraineurs was 22.0 ± 3.3 years.

There was a positive family history of migraine in a first degree relation in 32.4% while the overall mean pain intensity in the three months before the study was 4.7 with females having a higher score of 5.2 compared to 4.2 in males (p > 0.05).

67.6% of them use paracetamol

6.2% use non-steroidal anti-inflammatory drugs (NSAIDs)

16.2% did not specify the type of medications they use for prevention.

In the treatment of acute attack, majority of the

sufferers (64.8%) use only simple analgesics (paracetamol and

NSAID), 2.8% use ergot containing preparations while none reported having ever used triptans.

Not mentioned
Mustapha et al. 2019 Crosssectional descriptive study

213

184 (86.4%) females

and 29 (13.6%) males

26.8% (Male 27.6%, Female

2.2%)

Migraine without aura 5(21.1%)

Migraine with aura 12(5.6%)

Migraine with aura (MA) was

significantly (P < 0.01 more prevalent among the male students (27.6%) compared to the female

(2.2%).

Twelve (13.3%) of headache sufferers had history of refractive error.

Family history of

headache was present in 6 students (6.7%), who all had migraine headache.

The most common

trigger factors of headache attacks included sleep deprivation (65.6. %) and mental/physical

fatigue.

Only 8.9% of respondents in the

headache group sought medical care

66.7% self

medicated, while 33.3% treated their headaches

with bed rest.

Majority used

paracetamol (84.4%) while 25.6% and 16.7%

used ergot derivatives and non-steroidal anti

inflammatory drugs respectively during attacks

of headache. Only 1 (1.1%) was on preventive

medication (Amitriptyline).

Ofovwe, 2010 Cross-sectional Study

1679

809

(48.2%) were girls while 870

(51.8%)wereboys

13.5%. (Male 9.2%,

Female 18.2%)

Migraine without aura 190/328(57.9%)

Migraine with aura 37/328(11.3%)

Triggers

Emotional stress 72(23.3)

Sunlight/bright light 66(21.4)

Sleep deprivation 54(17.5)

Hunger 40(12.9)

Straining 31(10.0)

Odors (perfumes, smoke) 7(2.3)

Chocolate/milk/groundnut 2(0.7)

Others 37(12.0)

Relieving factors among the

migraineurs include analgesics in 172 (56.4%), lying

in dark, quiet rooms in 89 (29.2%), and eating in 44

(14.4%)

Not Mentioned
Sanya et al., 2017 Cross-sectional Study

1500

791

were males (52.7%) and 709 were females (47.3%).

2.4% (Females 57.5%, Males 42.5%). Fifty-eight students (3.9%) reported their headache to be unilateral in location, 33 (2.2%) had bilateral headaches, and 128 (8.5%) had frontal headaches. One hundred students (6.7%) had their headache associated with photophobia, 159 students (10.6%) had phonophobia, while 62 (4.1%) had nausea and vomiting. A total of 263 of the 356 students who experienced frequent headaches had their daily physical and school activities limited by headaches

Majority of the students (90.2%) used acetaminophen to treat their headaches while 2.8% used other types of nonsteroidal analgesics for their pain.

None of the students had seen a physician for a proper diagnosis of their headache; similarly, none was on antimigraine prophylactic medications.

Not Mentioned
Ojini et al., 2009 Cross-sectional survey

376

220 men and 156 women

24 (6.4)

Males 7 (3.2)

Females 17 (10.9)

Among students with migraine, headache was unilateral in 70.8%, throbbing in 62.5%, associated with nausea and vomiting in 47.8% and with both photophobia and phonophobia in 91.7%. All the students with migraine reported aggravation of headache with routine physical activity, whereas four (16.7%) reported the occurrence of an aura (wavy lines in two students, disturbed speech and blind spots in one student each).

Sought medical assistance8 (4.6)

Self-medication118 (68.2)

No medication or any other coping strategy26 (15.0)

Sleep∗53 (30.6)

Food1 (0.6)

Cold compress1 (0.6)

Most students (71.7%) used simple analgesics (67.6% took paracetamol, and 4.1% took aspirin).

Not Mentioned
Yunusa, 2016 Crosssectional Study

122

Female students were 73 (59.8%)

male students were 49 (40.2%)

28.7% (Females 50.8%, Males 40.2%) Of those who reported positive for migraine, 10 (29.4%) was left sided, 6 (17.6%) right sided, 10 (29.4%) both side of the head, while 7 (20.6%) reported generalized headache. The frequency of the migraine varied with some as frequent as 25 times a month. Fourteen (45.2%) reported the presence of sensory aura including visual and olfactory hallucination, while others complained of motor aura. The majority took acetaminophen. Not mentioned