Table 4.

Planned/actual accrual periods by method

All trial	Planned accrual period (years, IQR)	Actual accrual period (years, IQR)
Consideration of the patient accrual pace of past trials
Yes (n = 47)	3.3, IQR (2.6–4.4)	3.9, IQR (2.7–5.2)
No (n = 103)	3.0, IQR (2.1–4.0)	5.1, IQR (3.3–7.0)
Survey evaluation of the accrual pace of the participating institutions
Yes (n = 68)	3.0, IQR (2.5–4.0)	4.8, IQR (3.4–7.0)
No (n = 82)	3.0, IQR (2.5–4.0)	4.4, IQR (2.8–6.3)
Phase II
Consideration of the patient accrual pace of past trials
Yes (n = 19)	2.5, IQR (2.0–3.0)	2.8, IQR (1.8–3.6)
No (n = 30)	2.0, IQR (1.5–3.0)	3.0, IQR (1.9–3.5)
Phase III
Consideration of the patient accrual pace of past trials
Yes (n = 28)	4.0, IQR (3.8–5.0)	4.7, IQR (3.6–6.7)
No (n = 73)	3.0, IQR (3.0–4.0)	5.5, IQR (4.4–8.0)

These analyses targeted trials that had already been completed