Fig 6.
Synthesis of Pfizer compound 18. Reagents and conditions: (a) 50% T3P in DMF, DIPEA, 0°C to room temperature, 1 h. (b) LiOH in MeOH: THF: H2O (5:5:1), rt, 5 h. (c) 50% T3P in DMF, DIPEA, 0°C to room temperature, 1 h.
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