Fig 7.

Effects of compounds on CPE in Vero-E6 cells following SARS-CoV-2 infection. (A) Representative brightfield images of uninfected and SARS-CoV-2 USA-WA1/2020 variant-infected Vero-E6 cells following 4-day incubation in the absence or presence of representative compounds. Scale bars = 100 µm. (B) Dose-response curves of Mpro inhibitors and remdesivir on viral replication in Vero-E6 cells after 4-day infection. Data are presented as percent virus inhibition, with 0% denoting the viability of infected cells without drug and 100% denoting the viability of uninfected cells.