TABLE 1.

Mouse PK simulations

Regimen	Doses (mg/kg)	Data type	Data source
B	12.5, 25 single dose	PK simulation	Ernest et al. (11)
Pa	6, 9, 12, 18, 28.8, 50, 54, 162, 486 single dose; 100 daily for 4 or 8 weeks	PK simulation	Ernest et al. (11)