Table 1.
The demographics and clinical profile data of all CH patients
| Total N = 168 |
Ability to predict the upcoming CH bouts | p value* | ||
|---|---|---|---|---|
| Yes N = 86 (51.2%) |
No N = 82 (48.8%) |
|||
| Female sex, N (%) | 39 (23.2%) | 19 (22.1%) | 20 (24.4%) | 0.724 # |
| Age, mean (SD), years | 38.5 (11.0) | 37.9 (10.1) | 39.1 (11.9) | 0.492§ |
| Disease duration, median (IQR), years | 10 (5.0–17.0) | 12 (6.8–18) | 10 (4.0-15.3) | 0.073### |
| Total experienced CH bouts, median (IQR) | 8.5 (5.0–14.0) | 8.5 (6.0–14.0) | 8.5 (3.0–14.0) | 0.287### |
| Duration of bout, median (IQR), months | 1.5 (1.0–2.0) | 1.8 (1.0-2.1) | 1.5 (1.0–2.0) | 0.078### |
| Attacks per day in bout, mean (SD) | 2.1 (1.5) | 2.0 (1.2) | 2.1 (1.7) | 0.504§ |
| Attack duration without treatment, mean (SD), mins | 118.0 (160.5) | 112.2 (157.5) | 124.2 (164.4) | 0.632§ |
| CHSS score, mean (SD) | 5.96 (1.32) | 5.92 (1.27) | 6.00 (1.37) | 0.690§ |
| Circadian rhythmicity of CH attacks, % | 105 (62.5%) | 62 (72.1%) | 43 (53.4%) | 0.009# * |
| Seasonal rhythmicity of CH bouts, % | 127 (75.6%) | 64 (74.4%) | 63 (76.8%) | 0.716# |
| Comorbid migraine, n (%) | 34 (20.2%) | 21 (24.4%) | 13 (15.9%) | 0.167# |
| Out-of-bout shadow attacks, n (%) | 58 (34.5%) | 36 (41.9%) | 22 (26.8%) | 0.041 #* |
CHSS: Cluster Headache Severity Scale
* p < 0.05 was considered to indicate statistical significance
# The differences in these categorical variables between patients who were able and unable to predict upcoming bouts were analyzed by the chi-square test
## The differences in these categorical variables between patients who were able and unable to predict upcoming bouts were
analyzed by Fisher’s exact test
### The Mann‒Whitney U test was used to compare nonnormally distributed continuous variables, and p < 0.05 was
considered to indicate statistical significance
§ The differences in these continuous variables between patients who were able and unable to predict upcoming bouts were
analyzed by t tests