Table 2:
Perioperative variables
| Variable | No Chronic Kidney Disease (N = 321) |
Chronic Kidney Disease (N = 331) |
p |
|---|---|---|---|
| Intraoperative | |||
| Surgical Procedure* | 0.234 | ||
| Bipolar or Monopolar | 119 (37%) | 127 (38%) | |
| Nail | 116 (36%) | 133 (40%) | |
| Length of Surgery in Minutes (N=317/330) | 113 (50) | 108 (52) | 0.225 |
| Regional Anesthesia | 184 (57%) | 203 (61%) | 0.196 |
| Midazolam (mg/kg) (N=314/326) | 0.007(0.015) | 0.004 (0.012) | 0.013 |
| Propofol (mg/kg) (N=286/287) | 5 (5) | 5 (5) | 0.911 |
| Postoperative | |||
| Delirium on POD2 | 91 (28%) | 103 (31%) | 0.442 |
| Change in creatinine from ED to POD1, per mg/dl increase (N=307/325) | −0.04 (0.17) | −0.16 (0.36) | 0.000 |
| Time to Aldrete Score of 9 or Greater (min) (N=234/262) | 25 (44) | 29 (57) | 0.479 |
| Average Pain Score on PACU, No (%)Discharge (N=246/270) | 1 (2) | 1 (2) | 0.955 |
| Average Pain Score on POD1 (N=268/280) | 4 (3) | 3 (3) | 0.137 |
| Average Pain Score on POD2 (N=255/271) | 3 (3) | 3 (3) | 0.902 |
| Cumulative Opioid Dose (INTRAOP + PACU + POD1) mg/kg morphine equivalents (n=282/301) | 0.5 (0.5) | 0.4 (0.4) | 0.021 |
| ICU Days Postop (N=248/267) | 1 (3) | 1 (2) | 0.613 |
| RBC Units Transfused, No (%) perioperatively (N=283/297) | 1 (2) | 1 (2) | 0.952 |
| Hospital Length of Stay Days, Mean (SD) (N=315/326) | 6 (4) | 6 (4) | 0.751 |
| Discharge from Hospital Alive* | 316 (99%) | 316 (95%) | 0.012 |
| Discharge Location (N=306/310) | 0.880 | ||
| Home | 23 (7%) | 14 (5%) | |
| Skilled Rehabilitation | 275 (84%) | 251 (85%) |
*
N = 1 or 2 had missing value
**
N = 316 in the upper half and N = 327 in the chronic kidney disease group had data.
RBC= red blood cell. ICU= intensive care unit. PACU= post anesthesia care unit. POD= postoperative day. Intraop= intraoperative or intraoperatively. UTI= Urinary Tract Infection. Postop = postoperative or postoperatively. No =Number.