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. 2024 Sep 23;11:1467916. doi: 10.3389/fcvm.2024.1467916

Table 4.

Test characteristics for abnormal PET or relevant ischemia (>10%).

Sensitivity Specificity NPV PPV LR+ LR− DOR
Abnormal PET (SSS ≥ 4) <25th percentile 0.930 0.387 0.957 0.273 1.516 0.182 8.331
<50th percentile 0.800 0.573 0.921 0.316 1.872 0.349 5.362
CACS 0 0.975 0.297 0.979 0.255 1.387 0.085 16.250
CACS 1–9 0.960 0.154 0.918 0.280 1.135 0.262 4.332
CACS 1–99 0.818 0.463 0.881 0.343 1.524 0.393 3.879
Relevant ischemia (>10%) <25th percentile 0.982 0.355 0.995 0.135 1.523 0.051 29.960
<50th percentile 0.910 0.541 0.983 0.168 1.980 0.167 11.840
CACS 0 1.000 0.268 1.000 0.122 1.366 NA NA
CACS 1–9 0.976 0.139 0.976 0.137 1.134 0.173 6.565
CACS 1–99 0.861 0.427 0.957 0.173 1.503 0.325 4.631

NPV, negative predictive value; PPV, positive predictive value; LR+, positive likelihood ratio; LR-, negative likelihood ratio; DOR, diagnostic odds ratio.

Table indicates the test characteristics of different cut-offs (<25th percentile, <50th percentile, CACS 0, CACS 1–9, CACS 1–99) to diagnose/exclude abnormal PET (SSS ≥ 4) and relevant ischemia (SDS ≥ 7). A table including the 95% confidence intervals is displayed in the Supplementary Material (Supplementary Table S2).