Table 4.
Test characteristics for abnormal PET or relevant ischemia (>10%).
Sensitivity | Specificity | NPV | PPV | LR+ | LR− | DOR | ||
---|---|---|---|---|---|---|---|---|
Abnormal PET (SSS ≥ 4) | <25th percentile | 0.930 | 0.387 | 0.957 | 0.273 | 1.516 | 0.182 | 8.331 |
<50th percentile | 0.800 | 0.573 | 0.921 | 0.316 | 1.872 | 0.349 | 5.362 | |
CACS 0 | 0.975 | 0.297 | 0.979 | 0.255 | 1.387 | 0.085 | 16.250 | |
CACS 1–9 | 0.960 | 0.154 | 0.918 | 0.280 | 1.135 | 0.262 | 4.332 | |
CACS 1–99 | 0.818 | 0.463 | 0.881 | 0.343 | 1.524 | 0.393 | 3.879 | |
Relevant ischemia (>10%) | <25th percentile | 0.982 | 0.355 | 0.995 | 0.135 | 1.523 | 0.051 | 29.960 |
<50th percentile | 0.910 | 0.541 | 0.983 | 0.168 | 1.980 | 0.167 | 11.840 | |
CACS 0 | 1.000 | 0.268 | 1.000 | 0.122 | 1.366 | NA | NA | |
CACS 1–9 | 0.976 | 0.139 | 0.976 | 0.137 | 1.134 | 0.173 | 6.565 | |
CACS 1–99 | 0.861 | 0.427 | 0.957 | 0.173 | 1.503 | 0.325 | 4.631 |
NPV, negative predictive value; PPV, positive predictive value; LR+, positive likelihood ratio; LR-, negative likelihood ratio; DOR, diagnostic odds ratio.
Table indicates the test characteristics of different cut-offs (<25th percentile, <50th percentile, CACS 0, CACS 1–9, CACS 1–99) to diagnose/exclude abnormal PET (SSS ≥ 4) and relevant ischemia (SDS ≥ 7). A table including the 95% confidence intervals is displayed in the Supplementary Material (Supplementary Table S2).