Table 2. Effect of bafilomycin A1 on the fetal / neonatal development.
| Body weight (g) |
Littersize | |||
|---|---|---|---|---|
| Fetus | Neonate | Neonate | ||
| (PRG18) | (PRG21) | (PRG22–24) | (PRG22–24) | |
| Intact | 0.87 ± 0.01 a | 3.70 ± 0.05 a | 5.66 ± 0.06 a | 11.4 ± 0.9 |
| Vehicle | 0.79 ± 0.02 b | 3.52 ± 0.03 b | 5.64 ± 0.06 a | 10.5 ± 1.2 |
| Baf A1 625 pg | 0.79 ± 0.02 b | 3.47 ± 0.04 b | 5.34 ± 0.07 b | 10.3 ± 1.3 |
Intact mother rats and rats treated with Baf A1 (625 pg/rat) or vehicle on PRG15 were euthanized on PRG18 or PRG21 or left until delivery. The fetal body weight, neonatal weight, and litter size were also determined. Data are mean ± SEM (n = 15–120 in body weight, n = 12 in litter size). Different letters within the same column indicate significant differences (P < 0.05).