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. 2024 Oct 8;14:23496. doi: 10.1038/s41598-024-74635-7

Table 3.

Relationship between RFM and incident diabetes in different models.

Variable Model 1 (HR,95%CI, P) Model 2 (HR,95% CI, P) Model 3 (HR,95% CI, P)
All RFM 1.24 (1.21, 1.27) < 0.0001 1.13 (1.08, 1.19) < 0.0001 1.08 (1.02, 1.14) 0.0055
RFM (quartile)
Q1 ref ref ref
Q2 2.01 (1.46, 2.76) < 0.0001 0.98 (0.69, 1.38) 0.9003 0.72 (0.51, 1.03) 0.0719
Q3 5.19 (3.79, 7.11) < 0.0001 1.32 (0.87, 2.00) 0.1972 0.96 (0.63, 1.47) 0.8539
Q4 19.03 (12.27, 29.53) < 0.0001 1.65 (0.84, 3.25) 0.1484 1.18 (0.58, 2.39) 0.6543
P for trend < 0.0001 0.1033 0.6038
Female RFM 1.28 (1.22, 1.33) < 0.0001 1.19 (1.09, 1.30) < 0.0001 1.13 (1.04, 1.24) 0.0061
RFM (quartile)
Q1 ref ref ref
Q2 2.11 (0.76, 5.81) 0.1502 1.40 (0.50, 3.90) 0.5190 1.34 (0.48, 3.75) 0.5814
Q3 3.59 (1.39, 9.29) 0.0084 1.61 (0.60, 4.29) 0.3442 1.28 (0.47, 3.49) 0.6335
Q4 14.42 (6.17, 33.68) < 0.0001 2.86 (1.04, 7.88) 0.0419 1.63 (0.56, 4.72) 0.3711
P for trend < 0.0001 0.0240 0.3942
Male RFM 1.22 (1.18, 1.26) < 0.0001 1.11 (1.04, 1.18) 0.0023 1.05 (0.98, 1.13) 0.1511
RFM (quartile)
Q1 ref ref ref
Q2 1.40 (0.86, 2.30) 0.1791 0.96 (0.58, 1.60) 0.8867 0.60 (0.36, 1.01) 0.0547
Q3 1.99 (1.26, 3.15) 0.0034 0.97 (0.59, 1.59) 0.9002 0.50 (0.30, 0.85) 0.0107
Q4 6.09 (4.05, 9.15) < 0.0001 1.76 (1.04, 3.00) 0.0367 0.82 (0.47, 1.46) 0.5031
P for trend < 0.0001 0.0085 0.7088

Model 1: we did not adjust for any covariants.

Model 2: we adjusted for gender, age, BMI, alcoholic intake, smoking status, exercise habits, SBP, and DBP.

Model 3: we adjusted for gender, age, BMI, alcoholic intake, smoking status, exercise habits, SBP, DBP, ALT, AST, GGT, HDL-C, TC, TG, HbA1c, and FPG.

Note: The models were not adjusted for gender variables in both male and female models.

HR: hazard ratio; CI: confidence interval; Ref: Reference; RFM: relative fat mass.