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. 2024 Oct 8;14:23496. doi: 10.1038/s41598-024-74635-7

Table 4.

The result of the two-piecewise Cox proportional hazards regression model by gender.

Incident DM All participants
(HR, 95%CI, P)
Female
(HR, 95%CI, P)
Male
(HR, 95%CI, P)
Fitting model by standard linear regression 1.08 (1.02, 1.14) 0.0055 1.13 (1.04, 1.24) 0.0061 1.05 (0.98, 1.13) 0.1511
Fitting model by two-piecewise Cox proportional hazards regression
The inflection point of RFM 22.06 39.23 23.08
≤ Inflection point 0.97 (0.90, 1.05) 0.4941 1.11 (1.01, 1.21) 0.0256 0.98 (0.91, 1.06) 0.5899
> Inflection point 1.12 (1.06, 1.19) 0.0002 1.39 (1.17, 1.65) 0.0002 1.16 (1.06, 1.28) 0.0012
P for log-likelihood ratio test 0.002 0.009 0.002

Note 1: In all participants, we adjusted gender, age, BMI, alcoholic intake, smoking status, exercise habits, SBP, DBP, ALT, AST, GGT, HDL-C, TC, TG, HbA1c, and FPG.

Note 2: For female and male subgroups, we adjusted for age, BMI, alcoholic intake, smoking status, exercise habits, SBP, DBP, ALT, AST, GGT, HDL-C, TC, TG, HbA1c, and FPG.

HR: hazard ratios; CI: confidence; DM: diabetes mellitus; RFM: relative fat mass