Table 4.
Comparison of the variability due to batch effects, cell-type effects, and residuals among the three data sources used in this study, based on PVCA.a
| Data Source | Batch | Cell | Residual |
|---|---|---|---|
| Simulation (Average) | 0.078 | 0.027 | 0.895 |
| Simulation 21 | 0.249 | 0.002 | 0.750 |
| Simulation 85 | 0.016 | 0.077 | 0.907 |
| Bacher T-cell | 0.049 | 0.093 | 0.858 |
| Zilionis Mouse Lung | 0.023 | 0.113 | 0.863 |
a
For the simulated data, values are averaged over the 100 iterations. The simulation settings with the highest proportion of batch effects (21) and cell effects (85), respectively, are also shown to illustrate the range of the simulation settings. The values shown are proportions; rows that do not add up to 1 are due to rounding.