Table 2.
Changes in glycemic and body composition measures from baseline to post-LGL diet.
| Baseline | Post-LGL diet | p-value | |
|---|---|---|---|
| Body composition | |||
| Weight (kg) | 64.8 ± 3.3 (57.2, 72.3) |
64.0 ± 3.2 (56.9, 71.2) |
0.26 |
| BMI (kg/m2) | 24.1 ± 0.6 (22.6, 25.5) |
23.8 ± 0.6 (22.5, 25.1) |
0.23 |
| Total fat mass (gm) | 23,159 ± 2,681 (16,818, 29,498) |
22,133 ± 2,848 (15,398, 28,869) |
0.11 |
| Total lean mass (gm) | 43,545 ± 3,868 (34,398, 52,691) |
43,552 ± 3,980 (34,138, 52,965) |
0.99 |
| % fat mass | 34 ± 3.7 (25.4, 42.7) |
33 ± 3.9 (23.7, 42.4) |
0.09 |
| Trunk fat (gm) | 10,294 ± 1,449 (6,867, 13,720) |
9,805 ± 1,502 (6,253, 13,357) |
0.14 |
| % trunk fat | 30.7 ± 3.7 (22, 39.4) |
29.8 ± 4.0 (20.3, 39.3) |
0.18 |
| Fat mass index (FMI, kg/m2) | 8.6 ± 1.1 (6.1, 11.1) |
8.2 ± 1.1 (5.6, 10.9) |
0.16 |
| Lean mass index (LMI, kg/m2) | 15.8 ± 0.8 (14, 17.5) |
15.8 ± 0.8 (13.8, 17.8) |
0.68 |
| Appendicular lean mass index (ALMI, kg/m2) | 6.5 ± 0.5 (5.4, 7.6) |
6.6 ± 0.5 (5.5, 7.6) |
0.55 |
| Glycemic measures | |||
| HbA1c (%) | 5.7 ± 0.2 (5.2, 6.3) |
5.6 ± 0.2 (5.2, 6.1) |
0.55 |
| AG (mg/dL) | 127.1 ± 5.5 (114.8, 139.5) |
120.7 ± 3.1 (113.7, 127.7) |
0.16 |
| SD (mg/dL) | 29.8 ± 2.3 (24.6, 35.1) |
28.5 ± 1.5 (25.1, 31.9) |
0.96 |
| CV (%) | 23.2 ± 1.0 (21, 25.4) |
23.6 ± 1.1 (21.1, 26.2) |
0.58 |
| % time < 54 mg/dL | 0.2 ± 0.1 (0.05, 0.4) |
0.5 ± 0.2 (0.05, 0.9) |
0.36 |
| % time < 70 mg/dL | 1.0 ± 0.5 (0.1, 2) |
1.4 ± 0.4 (0.4, 2.4) |
0.28 |
| % time 70–180 mg/dL | 91.4 ± 2.6 (85.6, 97.2) |
94.2 ± 0.9 (92.2, 96.2) |
0.48 |
| % time 70–140 mg/dL | 74.2 ± 5.3 (62.3, 86) |
78.8 ± 5.4 (73.2, 84.4) |
0.51 |
| % time > 180 mg/dL | 7.6 ± 2.7 (1.6, 13.7) |
4.4 ± 0.8 (2.5, 6.4) |
0.17 |
| % time > 140 mg/dL | 24.8 ± 2.5 (12.6, 37.1) |
19.8 ± 2.5 (14.1, 25.5) |
0.28 |
| % time > 250 mg/dL | 1.1 ± 0.5 (0.2, 2.3) |
0.3 ± 0.1 (0.03, 0.6) |
0.39 |
| Questionnaire data | |||
| PAGI | 13.3 ± 2.6 (7, 19.6) |
8.7 ± 6.3 (0, 24.2) |
0.07 |
| PAC | 13.3 ± 5.7 (0.7, 27.2) |
5.3 ± 1.9 (0.7, 9.9) |
0.16 |
| Bristol | 3.7 ± 0.6 (2.1, 5.3) |
3.6 ± 0.4 (2.7, 4.5) |
0.87 |
| MAQ | 11,386 ± 6,188 (0, 25,818) |
12,358 ± 9,735 (0, 39,431) |
0.72 |
Data displayed as average ± standard error (95% confidence interval).
Weight, BMI, CGM measures, n = 10; DXA measures, n = 8; Questionnaire data n = 7.
LGL, low glycemic load; BMI, body mass index; AG, average glucose; SD, standard deviation; CV, coefficient of variation; PAGI, patient assessment of gastrointestinal symptoms; PAC, patient assessment of constipation; MAQ, modified activity questionnaire.