Table 3.
Description of the Study Population at Baseline RNFL Measurement (Mean ± SD or n [%])
| Characteristics | Included (n = 548) |
Nonincluded (n = 340) |
P Value |
|---|---|---|---|
| Mean ± SD or n (%) | |||
| Age | 82.4 ± 4.3 | 84.4 ± 5.0 | <0.001 |
| Sex | 0.05 | ||
| Male | 205 (37.4%) | 105 (30.9%) | |
| Female | 343 (62.6%) | 235 (69.1%) | |
| Smoking (pack-years) | n = 543 | n = 332 | 0.13 |
| Never smoked | 352 (64.8%) | 233 (70.2%) | |
| <20 | 98 (18.0%) | 48 (14.5%) | |
| ≥20 | 93 (17.1%) | 51 (15.4%) | |
| BMI (kg/m2) | n = 548 | n = 331 | 0.84 |
| [0, 18.5) | 3 (0.5%) | 5 (1.5%) | |
| [18.5,25) | 212 (38.7%) | 133 (40.2%) | |
| [25, 30) | 249 (45.4%) | 133 (40.2%) | |
| [30, 59] | 84 (15.3%) | 60 (18.1%) | |
| Social deprivation index | 0.6 ± 2.2 | 0.7 ± 2.2 | 0.57 |
| Plasma lipids (mmol/L) | |||
| LDL cholesterol | 3.7 ± 0.8 | 3.5 ± 0.8 | 0.08 |
| HDL cholesterol | 1.6 ± 0.4 | 1.6 ± 0.4 | 0.55 |
| Triglycerides | 1.2 ± 0.6 | 1.3 ± 0.7 | 0.27 |
| Diabetes | 40 (7.3%) | 30 (8.8%) | 0.12 |
| Hypertension | 396 (72.3%) | 267 (78.5%) | 0.03 |
| Cardiovascular diseases | 43 (7.8%) | 35 (10.3%) | 0.25 |
| Mediterranean diet score | 10.6 ± 2.1 | 10.6 ± 2.0 | 0.88 |
| Lipid-lowering medication | 181 (33.0%) | 102 (30.0%) | 0.40 |
| Family history of glaucoma | n = 537 | n = 203 | |
| 73.0 (13.6%) | 21.0 (10.3%) | 0.29 | |
| Axial length | n = 321 | n = 119 | |
| Right eye | 23.5 ± 1.2 | 23.8 ± 1.9 | 0.09 |
| Left eye | 23.4 ± 1.1 | 23.7 ± 1.7 | 0.16 |
| Intraocular pression | n = 542 | n = 330 | |
| Right eye | 13.4 ± 2.3 | 13.3 ± 2.3 | 0.40 |
| Left eye | 13. 6 ± 2.4 | 13.4 ± 2.2 | 0.21 |
| Global peripapillary RNFL thickness (μm) | n = 1062 eyes 89.8 ± 14.5 |
- | - |
BMI = body mass index; HDL = high-density lipoprotein; LDL = low-density lipoprotein; RNFL = retinal nerve fiber layer; SD = standard deviation.
Alienor study, 2009 to 2020.
Bold values represent statistically significant results.