Table 2.
Klebsiella pneumoniae carbapenems and ceftazidime-avibactam resistance rate by mechanism.
| KPN strains n (%) | non-adjusted OR | CI95% | p value | ||
|---|---|---|---|---|---|
| P1 | P2 | ||||
| Carbapenem-resistant KPN | 73 (59.3) | 131 (76) | 2.2 | 1.3-3.6 | <.001 |
| Ceftazidime-avibactam-resistant KPN | 34 (32) | 67 (46.5) | 1.8 | 1.1-3.1 | <.02 |
| blaMBL (total)* | 34 (32.1) | 65 (45.1) | 1.7 | 1.1-2.9 | <.04 |
| blaMBL and blaEsBL | 31 (29.2) | 53 (36.8) | 1.4 | 0.8-2.4 | .2 |
| blaMBL and blaKPC | 3 (2.8) | 12 (8.3) | 3.1 | 0.8-11.3 | <.07 |
| blaKPC | 34 (27.6) | 57 (33.1) | 1.3 | 0.8-2.2 | .3 |
| blaOXA-163 | 3 (1.7) | 3 (2.4) | 0.7 | 0.1-3.6 | .7 |
| blaESBL and impermeability | 2 (2.1) | 4 (2.3) | 1.4 | 0.3-7.9 | .7 |
*
It includes KPN strains that harbor at least blaMBL, although this is not the only mechanism of resistance against β-lactams.