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. 2024 Sep 25;11:1441847. doi: 10.3389/fnut.2024.1441847

Table 2.

Summary table of subgroup analysis.

Mortality ICU admission Length of hospital stay Endotracheal intubation
Subgroup criteria Analysis type RR (95% CI) I2 p value RR (95% CI) I2 p value MD (95% CI) I2 p value RR (95% CI) I2 p value
Total analysis 0.72 (0.54–0.94) 54% 0.02 0.58 (0.38–0.88) 74% 0.01 −1.00 (−2.16 to 0.16) 63% 0.13 0.78 (0.56–1.08) 60% 0.13
Subgroup by administration method Single-dose 0.88 (0.69–1.12) 21% 0.3 0.79 (0.61–1.03) 22% 0.08 −1.11 (−2.35 to 0.13) 53% 0.08 −0.10 (−0.23 to 0.03) 42% 0.13
Continuous dose 0.53 (0.34–0.83) 55% 0.006 0.44 (0.22–0.90) 74% 0.02 −0.50 (−2.23 to 1.22) 69% 0.57 −0.00 (−0.04 to 0.04) 45% 0.87
Subgroup by dosage ≥100,000 IU 0.85 (0.71–1.02) 1% 0.07 0.86 (0.60–1.24) 54% 0.42 −0.91 (−1.83 to 0.01) 57% 0.05 0.59 (0.32–1.09) 38% 0.09
<100,000 IU 0.30 (0.21–0.44) 0% <0.0001 0.31 (0.21–0.47) 0% 0.001 −0.97 (−3.24 to 1.29) 48% 0.4 0.96 (0.39–2.35) 34% 0.93
Subgroup by baseline vitamin D status Vitamin D deficient (25OHD < 30 ng/mL) 0.73 (0.59–0.89) 0% 0.002 0.63 (0.42–0.93) 0% 0.02 −0.62 (−2.17 to 0.92) 72% 0.43 0.92 (0.61–1.37) 36% 0.67
No baseline restriction 0.73 (0.46–1.15) 73% 0.18 0.59 (0.32–1.11) 86% 0.1 −0.25 (−1.12 to 0.62) 75% 0.57 0.78 (0.34–1.80) 74% 0.57