Age (mean ± SD, min–max, median) |
63.3 ± 9.7 (36–88, 63) |
65.5 ± 10.4 (20–91, 66) |
65 ± 10.2 (20–91, 66) |
BMI (mean ± SD, min–max, median) |
26.2 ± 4.7 (17.6–46.8, 25.2) |
26.7 ± 5.1 (14.4–54.4, 26) |
26.6 ± 5 (14.4–54.4, 25.8) |
Time since diagnosis (years) (mean ± SD, min–max, median) |
9.0 ± 6.9 (0.2–39.1, 7.0) |
8.8 ± 6.9 (0.2–40.4, 7.0) |
8.9 ± 6.9 (0.2–40.4, 7.0) |
TNM classification of the tumor at time of primary diagnosis—T, n (%) |
X |
9 (2.8) |
66 (6.0) |
75 (5.3) |
1 |
95 (29.1) |
316 (28.7) |
411 (28.8) |
2 |
155 (47.4) |
450 (40.9) |
605 (42.4) |
3 |
38 (11.6) |
121 (11.0) |
159 (11.1) |
4 |
30 (9.2) |
148 (13.4) |
178 (12.5) |
Missing |
5 |
7 |
12 |
TNM tumor stadium at time of primary diagnosis—N, n (%) |
X |
12 (3.7) |
101 (9.2) |
113 (7.9) |
0 |
103 (31.4) |
297 (27.0) |
400 (28.0) |
1 |
111 (33.8) |
384 (34.9) |
495 (34.6) |
2 |
54 (16.5) |
169 (15.3) |
223 (15.6) |
3 |
48 (14.6) |
150 (13.6) |
198 (13.9) |
Missing |
4 |
7 |
11 |
TNM tumor stadium at time of primary diagnosis—M, n (%) |
X |
26 (8.0) |
91 (8.3) |
117 (8.2) |
0 |
224 (68.7) |
717 (65.2) |
941 (66.0) |
1 |
76 (23.3) |
292 (26.5) |
368 (25.8) |
Missing |
6 |
8 |
14 |
Grading, n (%) |
G1 |
16 (5.1) |
50 (4.8) |
66 (4.8) |
G2 |
222 (70.5) |
694 (66.2) |
916 (67.2) |
G3 |
75 (23.8) |
303 (28.9) |
378 (27.7) |
G4 |
2 (0.6) |
2 (0.2) |
4 (0.3) |
Missing |
17 |
59 |
76 |
Histological subtype, n (%) |
Invasive ductal |
215 (67.2) |
744 (69.7) |
959 (69.1) |
Invasive lobular |
65 (20.3) |
229 (21.5) |
294 (21.2) |
Other subtypes |
40 (12.5) |
94 (8.8) |
134 (9.7) |
Missing |
12 |
41 |
53 |
Estrogen receptor, n (%) |
Negative |
7 (2.1) |
23 (2.1) |
30 (2.1) |
Positive |
324 (97.9) |
1084 (97.9) |
1408 (97.9) |
Missing |
1 |
1 |
2 |
Progesterone receptor, n (%) |
Negative |
79 (23.9) |
255 (23.0) |
334 (23.2) |
Positive |
249 (75.2) |
839 (75.8) |
1088 (75.7) |
Unknown |
3 (0.9) |
13 (1.2) |
16 (1.1) |
Missing |
1 |
1 |
2 |
Metastases at primary diagnosis, n (%) |
No |
270 (81.8) |
869 (78.9) |
1139 (79.5) |
Yes |
60 (18.2) |
233 (21.1) |
293 (20.5) |
Missing |
2 |
6 |
8 |
Metastases localization, n (%) |
Visceral metastases (lung, liver, CNS) |
130 (39.4) |
432 (39.1) |
562 (39.1) |
Visceral and bone metastases |
65 (19.7) |
278 (25.1) |
343 (23.9) |
Visceral without bone metastases |
65 (19.7) |
154 (13.9) |
219 (15.3) |
Therapy line, n (%) |
1st line |
98 (29.5) |
310 (28.0) |
408 (28.3) |
2nd line |
111 (33.4) |
339 (30.6) |
450 (31.3) |
3rd line |
58 (17.5) |
217 (19.6) |
275 (19.1) |
4th line |
32 (9.6) |
122 (11.0) |
154 (10.7) |
5th line (and later) |
33 (9.9) |
120 (10.8) |
153 (10.6) |
Prior antineoplastic surgery, n (%) |
309 (93.1) |
1011 (91.2) |
1320 (91.7) |
Prior antineoplastic radiation, n (%) |
278 (83.7) |
897 (81.0) |
1175 (81.6) |