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. 2024 Oct 8;22:442. doi: 10.1186/s12916-024-03671-x

Table 1.

Patient characteristics. Data are presented as mean ± SD and as absolute numbers and percentages of category

Godin: active (N = 332) Godin: insufficiently active (N = 1108) Total (N = 1440)
Age (mean ± SD, min–max, median) 63.3 ± 9.7 (36–88, 63) 65.5 ± 10.4 (20–91, 66) 65 ± 10.2 (20–91, 66)
BMI (mean ± SD, min–max, median) 26.2 ± 4.7 (17.6–46.8, 25.2) 26.7 ± 5.1 (14.4–54.4, 26) 26.6 ± 5 (14.4–54.4, 25.8)
Time since diagnosis (years) (mean ± SD, min–max, median) 9.0 ± 6.9 (0.2–39.1, 7.0) 8.8 ± 6.9 (0.2–40.4, 7.0) 8.9 ± 6.9 (0.2–40.4, 7.0)
TNM classification of the tumor at time of primary diagnosis—T, n (%)
 X 9 (2.8) 66 (6.0) 75 (5.3)
 1 95 (29.1) 316 (28.7) 411 (28.8)
 2 155 (47.4) 450 (40.9) 605 (42.4)
 3 38 (11.6) 121 (11.0) 159 (11.1)
 4 30 (9.2) 148 (13.4) 178 (12.5)
 Missing 5 7 12
TNM tumor stadium at time of primary diagnosis—N, n (%)
 X 12 (3.7) 101 (9.2) 113 (7.9)
 0 103 (31.4) 297 (27.0) 400 (28.0)
 1 111 (33.8) 384 (34.9) 495 (34.6)
 2 54 (16.5) 169 (15.3) 223 (15.6)
 3 48 (14.6) 150 (13.6) 198 (13.9)
Missing 4 7 11
TNM tumor stadium at time of primary diagnosis—M, n (%)
 X 26 (8.0) 91 (8.3) 117 (8.2)
 0 224 (68.7) 717 (65.2) 941 (66.0)
 1 76 (23.3) 292 (26.5) 368 (25.8)
 Missing 6 8 14
Grading, n (%)
 G1 16 (5.1) 50 (4.8) 66 (4.8)
 G2 222 (70.5) 694 (66.2) 916 (67.2)
 G3 75 (23.8) 303 (28.9) 378 (27.7)
 G4 2 (0.6) 2 (0.2) 4 (0.3)
 Missing 17 59 76
Histological subtype, n (%)
 Invasive ductal 215 (67.2) 744 (69.7) 959 (69.1)
 Invasive lobular 65 (20.3) 229 (21.5) 294 (21.2)
 Other subtypes 40 (12.5) 94 (8.8) 134 (9.7)
 Missing 12 41 53
Estrogen receptor, n (%)
 Negative 7 (2.1) 23 (2.1) 30 (2.1)
 Positive 324 (97.9) 1084 (97.9) 1408 (97.9)
 Missing 1 1 2
Progesterone receptor, n (%)
 Negative 79 (23.9) 255 (23.0) 334 (23.2)
 Positive 249 (75.2) 839 (75.8) 1088 (75.7)
 Unknown 3 (0.9) 13 (1.2) 16 (1.1)
 Missing 1 1 2
Metastases at primary diagnosis, n (%)
 No 270 (81.8) 869 (78.9) 1139 (79.5)
 Yes 60 (18.2) 233 (21.1) 293 (20.5)
 Missing 2 6 8
Metastases localization, n (%)
 Visceral metastases (lung, liver, CNS) 130 (39.4) 432 (39.1) 562 (39.1)
 Visceral and bone metastases 65 (19.7) 278 (25.1) 343 (23.9)
 Visceral without bone metastases 65 (19.7) 154 (13.9) 219 (15.3)
Therapy line, n (%)
 1st line 98 (29.5) 310 (28.0) 408 (28.3)
 2nd line 111 (33.4) 339 (30.6) 450 (31.3)
 3rd line 58 (17.5) 217 (19.6) 275 (19.1)
 4th line 32 (9.6) 122 (11.0) 154 (10.7)
 5th line (and later) 33 (9.9) 120 (10.8) 153 (10.6)
 Prior antineoplastic surgery, n (%) 309 (93.1) 1011 (91.2) 1320 (91.7)
 Prior antineoplastic radiation, n (%) 278 (83.7) 897 (81.0) 1175 (81.6)