Table 1.
Currently known about nanomaterials in diseases
| Category | Diseases | Nanomaterials | Function | Reference |
|---|---|---|---|---|
| Cancer | Bladder cancer | MnO2 based nanomaterials | Block autophagic flux | [108] |
| Co3 O4 NPs | Inhibit autophagy | [109] | ||
| Ovarian cancer | ZnO NPs | Lead to mitochondrial damage via ROS and induce autophagy | [110] | |
| Lung epithelial cancer | IO NPs | Induce autophagy | [111] | |
| Breast cancer | Au NPs | Active autophagy | [112] | |
| Glioma | Au NPs | Drug delivery systems | [115] | |
| Prostate cancer | mPDA NPs | [116] | ||
| Breast cancer | NPs loading autophagy-inhibiting microRNAs | [117] | ||
| Neurological diseases | Alzheimer’s disease | A quercetin (autophagy inducer)-modified polysorbate 80 (P-80)-coated AuPd core-shell nanostructure | Promote the fusion of autophagosomes and lysosomes | [123] |
| Autoimmune diseases | Treating autoimmune diseases | Se @Ru NPs by inducing the formation of iNOS | Stimulate NO production | [125] |
| Infectious disease | Chlamydia trachomatis | PDGFR-β siRNA-PEI-PLGA-PEG NP | Induce cellular autophagy | [129] |
| Intestinal viruses | RES NPs | Inhibit viral replication and inflammatory responses | [133] | |
| HIV | T NPs | Induce autophagy | [134] |