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. 2024 Oct 8;22:608. doi: 10.1186/s12951-024-02875-w

Table 2.

Nanomaterials eliminate Mtb

Nanomaterials Function Reference
ZnO NPs Low doses: promote autophagy and the expression of M1 macrophage polarization markers decreases. [141]
High doses: induce ferroptosis
Se NPs Energy transduction disruption, increase ROS production, membrane depolarization, and membrane disruption [142]
ZnO-Se NPs Promoted autophagy, increase intracellular ROS, disrupt mitochondrial membrane potential and inhibit PI3K/Akt/mTOR signaling pathway [39]
(RB-NPs)-GP Promote antimicrobial autophagy and apoptosis, induce reactive oxygen species and reactive nitrogen species [148]
GO NPs Regulate apoptosis and autophagy also increase the formation of reactive oxygen species [151, 152]
Drug delivery system
GO-PEG-MAN NPs Improve intracellular drug contents and maintain high drug concentration [153]
ISCur NPs Induce apoptosis and promote phagosome-lysosome fusion [156]
Anti- TGF -β1 siRNAs Promote autophagy [158]