Table 2.
Nanomaterials eliminate Mtb
| Nanomaterials | Function | Reference |
|---|---|---|
| ZnO NPs | Low doses: promote autophagy and the expression of M1 macrophage polarization markers decreases. | [141] |
| High doses: induce ferroptosis | ||
| Se NPs | Energy transduction disruption, increase ROS production, membrane depolarization, and membrane disruption | [142] |
| ZnO-Se NPs | Promoted autophagy, increase intracellular ROS, disrupt mitochondrial membrane potential and inhibit PI3K/Akt/mTOR signaling pathway | [39] |
| (RB-NPs)-GP | Promote antimicrobial autophagy and apoptosis, induce reactive oxygen species and reactive nitrogen species | [148] |
| GO NPs | Regulate apoptosis and autophagy also increase the formation of reactive oxygen species | [151, 152] |
| Drug delivery system | ||
| GO-PEG-MAN NPs | Improve intracellular drug contents and maintain high drug concentration | [153] |
| ISCur NPs | Induce apoptosis and promote phagosome-lysosome fusion | [156] |
| Anti- TGF -β1 siRNAs | Promote autophagy | [158] |