Table 1.
Comparison of firing properties between WT and APP/PS1 place cells in CA1 and CA3. Mann-Whitney U test between WT and APP/PS1.
| Parameters | Session | CA1 | CA3 | ||
|---|---|---|---|---|---|
| WT | APP/PS1 | WT | APP/PS1 | ||
| Spikes | SE1 | 1365.2 ±203.3 | 1035.5 ±121.8 | 1172.0 ±248.4 | 1326.9 ±190.3 |
| SE2 | 1677.2 ±233.1 | 1187.2 ±148.8 | 1332.8 ±405.9 | 1075.1 ±172.8 | |
| Mean Firing rate (Hz) | SE1 | 1.13 ±0.16 | 0.86 ±0.10 | 0.97 ±0.20 | 1.10 ±0.15 |
| SE2 | 1.39 ±0.19 | 0.98 ±0.12 | 1.11 ±0.33 | 0.89 ±0.14 | |
| Max firing rate (Hz) | SE1 | 4.88 ±0.67 | 2.90 ±0.21 | 3.37 ±0.42 | 3.54 ±0.64 |
| SE2 | 5.14 ±0.72 | 2.93 ±0.25 * | 3.31 ±0.81 | 2.64 ±0.48 | |
| In-field firing rate (Hz) | SE1 | 3.08 ±0.44 | 1.88 ±0.15 | 2.21 ±0.34 | 2.25 ±0.33 |
| SE2 | 3.48 ±0.49 | 2.02 ±0.19 * | 2.34 ±0.62 | 1.87 ±0.27 | |
| Out-field firing rate (Hz) | SE1 | 0.37 ±0.06 | 0.39 ±0.06 | 0.29 ±0.07 | 0.28 ±0.04 |
| SE2 | 0.50 ±0.09 | 0.46 ±0.08 | 0.45 ±0.17 | 0.20 ±0.04 | |
| Selectivity | SE1 | 1.04 ±0.03 | 0.87 ±0.05 | 0.99 ±0.04 | 0.96 ±0.04 |
| SE2 | 0.99 ±0.03 | 0.82 ±0.05 | 0.94 ±0.04 | 0.99 ±0.04 | |
P<0.05.