Neutralization of SARS-CoV-2 variants circulating in mid-2024 by mAbs. A. Neutralization curves of mAbs in S-Fuse cells. Dose-response analysis of neutralization of the indicated variants by S309/Sotrovimab, VYD222/Pemivibart, AZD3152/Sipavibart, and SA55. Data are presented as mean ± standard deviation of 2–3 independent experiments. B. Neutralization curves of mAbs in IGROV-1 cells. Dose-response analysis of neutralization of the indicated variants by S309/Sotrovimab, VYD222/Pemivibart, AZD3152/Sipavibart, and SA55. Data are presented as mean ± standard deviation of 2–3 independent experiments. C. EC50 values (in ng/mL) for each mAb against the indicated viral strains in the 2 cell lines. “- ”: no antiviral activity.